It can be safe if you're using it over your own LAN, like if you have multiple servers at a location that talk to each other.
0.3.13 RC1 is available for Windows:
http://www.bitcoin.org/download/bitcoin-0.3.13-rc1-win32-setup.exe
BitcoinTalk
#6From:
satoshi
Subject:
Re: Remote RPC access
Date: